Seth LaSherus managed to escape being forced back to his unearthly level and now is in search of a new weapon to wield against the man who has been his greatest foe throughout the centuries.
In the wild and untamed swamps of Louisiana, he locates the tool that will assure his success.
The Vodun hold a sacred oath to protect their magic from those who would use it for their own evil ends. Countess Vesper has served as Caplata and protector of Vodun magic for almost a century and has trained her great-grand-daughter, Linda, to take up her mantle for the next generation. Linda is forced to call the only person that may be able to help; a man only known by the name Walker.
In the meantime, Val Rousse, a young, pregnant blind woman, terrified in knowing that her daughter was sired by Stephan, a wolf demon from the hell dimension, is invited to give a piano concert in New Orleans unaware that she and her child are just instruments in Seth's evil plan.
Once again, Walker is called to a mission to defend his friends, Val, Brenda, and Matt against the maniacal Seth while unaware that a new adversary is watching his every move.